Mechanisms underlying changes in hippocampal information processing by neuromodulation
Our project scrutinises how serotonergic neuromodulation impacts hippocampal information processing. We investigate to what extent serotonergic input controls excitation/inhibition balance within the hippocampus, in a state-dependent manner, and how this contributes to subcortical and hippocampal information processing. Serotonergic neuromodulation is examined on several levels: behavioural experiments in conjunction with optogenetics will elucidate the impact of 5-HT on memory and sensory information processing, whereas electrophysiological recordings in combination with state-of-the-art imaging techniques will reveal the underlying mechanisms.
Prof. Dr. Olivia Masseck
Faculty 2 - Biology/Chemistry
NW2, Raum B 4115
Leobener Straße 5