Project B10 (Herlitze / Manahan-Vaughan)
Cerebellar-Hippocampal regulation of sensory information processing and cognition
Summary
The goal of this project is to explore and characterise cerebellar regulation of sensory information processing leading to spatial representations and declarative memory formation in the hippocampus. We use optogenetic, cellular imaging and tracing techniques to identify the specific projections and to control and modulate the output activity from the cerebellum to the hippocampus. We also use in vivo electrophysiological recordings from freely exploring mice during optogenetic manipulation to study the role of cerebellar activity on spatial information processing in the hippocampus and on hippocampus-mediated goal-directed navigation behaviour.
Principal Investigators
Project B10
Prof. Dr. Stefan Herlitze
General Zoology and Neurobiology
Faculty of Biology and Biotechnology
Ruhr-Universität Bochum
ND 7 / 32
Universitätsstr. 150
44801 Bochum
Phone: +49 - (0)234 - 32 - 24363
Fax: +49 - (0)234 - 32 - 14185
Projects B1, B3, B10, Z1, Z2
Prof. Dr. Denise Manahan-Vaughan
Neurophysiology
Medical Faculty
Ruhr-Universität Bochum
MA 4 / 150
Universitätsstr. 150
44801 Bochum
Phone: +49 - (0)234 - 32 - 22042
Fax: +49 - (0)234 - 32 - 14490